The correct use of weight loss peptides should be under the guidance of a doctor, combined with diet and exercise. Its core function is to suppress appetite and regulate metabolism. It is suitable for obese individuals with a BMI ≥ 27 and comorbidities, or a BMI ≥ 30. It is mainly administered via subcutaneous injection, with the dosage gradually increased to reduce side effects.
Weight loss peptides are not a shortcut to instant weight loss, but rather a medical approach requiring scientific management. The following is a detailed explanation of their effects, suitable populations, and usage methods:
Core Effects of Weight Loss Peptides
Weight loss peptides (such as liraglutide, smegglutide, and telpoglutide) are GLP-1 receptor agonists, primarily working through the following mechanisms:
Suppressing Appetite: Acting on the brain's satiety center to reduce hunger.
Delaying Gastric Emptying: Slowing down food digestion and prolonging satiety time.
Regulating Blood Sugar and Metabolism: Improving insulin sensitivity and reducing the risk of fat accumulation.
Clinical weight loss data: Smegglutide resulted in an average weight loss of 17% (approximately 16.8 kg). Telboride achieved a maximum weight loss of 20.9% in trials. Liraglutide, at a daily dose of 1.8 mg, resulted in a weight loss of over 2.6 kg (within 12 weeks).